British scientists may have accidentally discovered a new type of cell that kills most cancers. The new discovery could be a huge breakthrough in the search for a universal cure for cancer, writes the British newspaper The Telegraph.
An immune cell that combats cancerous cells and ignores healthy cells sounds promising indeed. I hope their research holds up to scrutiny by other researchers and medical professionals.
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As The Telegraph reports, “Researchers at Cardiff University were analyzing blood from a bank in Wales, looking for immune cells that could fight bacteria, when they found an entirely new type of T-cell. That new immune cell carries a never-before-seen receptor which acts like a grappling hook, latching on to most human cancers, while ignoring healthy cells.”
What makes this new discovery so exciting is that prior therapies, referred to as CAR-T and TCR-T therapies, which use immune cells to attach to HLA molecules on cancer cells’ surface, fight cancer but are incapable of fighting solid tumors. As The Telegraph points out, HLA molecules vary in people, but the new therapy attaches to a molecule called MR1, which does not vary in humans, which gives it the chance of fighting most cancers and additionally means people could share the treatment, allowing banks of the cells to be stored and thus be offered quickly to people suffering from the disease.
Immune cells from the new treatment have killed lung, skin, blood, colon, breast, bone, prostate, ovarian, kidney and cervical cancer cells. The study stated:
Human leukocyte antigen (HLA)-independent, T cell-mediated targeting of cancer cells would allow immune destruction of malignancies in all individuals. Here, we use genome-wide CRISPR-Cas9 screening to establish that a T cell receptor recognized and killed most human cancer types via the monomorphic MHC class-I related protein, MR1, while remaining inert to noncancerous cells … These finding offer opportunities for HLA-independent, pan-cancer, pan-population immunotherapies. More
It sounds like the breakthrough immunotherapy we were waiting for. Amazing find but there’s still many years of research to develop it as a treatment, but will it get shot down by big pharmaceutical companies before then?
Big Pharma will figure out how to charge a fortune for it and make it nearly impossible for the average person to get a hold of it.Don't forget to Like Godfather Politics on Facebook and Twitter, and visit our friends at RepublicanLegion.com.
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